semaglutide and kidney problems Semaglutides Are Poised to Remake Chronic Disease Care Effects of Semaglutide on CKD

Bethesda, MD, USA: National Institutes of Health (2007)

Common Mild Side Effects These typically appear during the first few weeks of use: Increased hunger Especially with Ipamorelin due to ghrelin receptor stimulation Mild water retention Often resolves after the body adjusts Tingling or numbness Usually in fingers or hands (transient) Lightheadedness More common with higher doses or low-carb diets Most of these effects are dose-dependent and subside within a week or two

Dec 22 2022;13(6):2357-2405

The study is assessing both subcutaneous and intravenous formulations of the drug and comparing it against placebo, looking primarily at the clearance of amyloid plaques